pentobarbital will decrease the extent or outcome of etravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
fentanyl transmucosal and pentobarbital both enhance sedation. Prevent or Use Alternate Drug. Restrict use to patients for whom choice procedure options are inadequate
pentobarbital will decrease the level or influence of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will decrease the level or influence of fludrocortisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital decreases levels of elvitegravir/cobicistat/emtricitabine/tenofovir DF by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. May perhaps bring about loss of virologic reaction and doable resistance.
Watch Intently (1)pentobarbital will lower the level or result of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
buprenorphine, long-acting injection and pentobarbital both boost sedation. Prevent or Use Alternate Drug. Restrict use to patients for whom substitute treatment method selections are inadequate
pentobarbital will decrease the extent or outcome of dexamethasone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Therapy must get more info be administered with caution, if whatsoever, to patients who will be mentally depressed, have suicidal tendencies, or background of drug abuse
Keep an eye on Intently (one)pentobarbital will reduce the level or outcome of fentanyl transdermal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to some lessen in fentanyl plasma concentrations, deficiency of efficacy or, probably, improvement of a withdrawal syndrome within a affected person that has designed physical dependence to fentanyl. Just after halting a CYP3A4 inducer, as the effects of your inducer decline, the fentanyl plasma focus will boost which could improve or prolong both the therapeutic and adverse effects.
pentobarbital will lower the level or result of itraconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
pentobarbital will minimize the extent or result of rabeprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unknown.
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Contraindicated (1)pentobarbital will decrease the extent or effect of cobimetinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Stay away from coadministration. Strong or reasonable CYP3A inducers may lessen cobimetinib systemic exposure by >eighty% and decrease its efficacy.